Preimplantation Genetic Testing for Aneuploidy: PGT-A
For people using IVF, it all comes down to one exciting moment: the embryo transfer. Choosing which embryo is “most likely to succeed” requires experience, skill and collaboration with our IVF embryology team. In some cases, it makes sense to get additional genetic information about your embryos, so that we can select the best one for transfer. If you’re looking for PGT in Nashville, you’ll be glad to know that we offer the most advanced preimplantation genetic testing available today, including PGT-A.
What is PGT-A?
The “A” in PGT-A stands for “aneuploidy,” which refers to an abnormal chromosome count. This genetic test can detect aneuploidy in embryos. A “euploid” embryo has the normal number of chromosomes: 46. Of those, 23 come from the mother, and 23 come from the father. If too many or too few chromosomes are present, the embryo is aneuploid.
Embryos with aneuploidy often fail to implant, or if they do implant, they may fail to develop normally, resulting in miscarriage. In some cases, aneuploid embryos become babies with chromosome disorders, such as Down syndrome, Trisomy 13, or Fragile X syndrome, among many others. Because PGT-A can detect chromosome problems before embryo transfer, this type of preimplantation genetic testing lets us choose only chromosomally normal embryos that will give you the best chance of a successful pregnancy and healthy child.
Do I really need preimplantation genetic testing?
While PGT-A can provide valuable information for any hopeful parent, it’s especially important to consider in certain cases. For example, in cases of unexplained infertility, advanced maternal age, recurrent miscarriage, repeated IVF failure, or family history of chromosome disorders, we may recommend this test to put you on a faster path to pregnancy.
Your Nashville Fertility Center reproductive endocrinologist will be happy to discuss whether PGT-A or PGT-A+ is right for you. If you are interested in learning more about PGT in Nashville, please contact us to schedule a consultation.
